T H E S C I E N C E I N S I D E T H E V I A L
Unmodified hyaluronic acid engineered to preserve its native molecular structure. No aggressive crosslinkers, no thermal treatment — pure molecular integrity preserved from fermentation to vial.
Explore productsThe technology
Trust your skin, awaken its potential for natural hydric self-filling. Elevate your natural beauty, respecting your essence.
Our technology is built on a non-interventionist biotechnology process under GMP and ISO 13485 standards.
By refusing to apply aggressive chemical crosslinking or high-temperature treatments, we preserve the native conformation and high molecular weight of the hyaluronic acid.
The result is a rare category in aesthetic medicine: a pure, non-modified HA that behaves exactly like endogenous HA.
This ensures a highly predictable pharmacokinetic and pharmacodynamic behavior with clean clinical outcomes.
Pillar 01 — Multi-Molecular weight synergy
Our advanced formulations combine Low, Medium, and High molecular weight HA (ranging from 300 kDa up to 2500 kDa).
This diverse architectural spectrum allows precise targeting of different skin levels: from superficial hydration and fine-line smoothing to deep dermis turgor, ensuring comprehensive cutaneous biostimulation.
Molecular Role: Its smaller molecular size allows deep tissue penetration and direct interaction with key cellular receptors, such as CD44
Clinical Benefits: Triggers fibroblast activation, stimulates endogenous collagen and elastin synthesis, and promotes extracellular matrix remodeling
Associated Product: HA MD Aqua 20
4 mechanisms
01Layer-by-layer
hydration
High molecular weight HA forms a protective, highly viscoelastic film on the stratum corneum to lock in moisture, while lower molecular weights penetrate deeper to quench the dermis.
02Fibroblast &
Elastin activation
By binding to vital CD44 receptors, our pure HA stimulates the natural production of fibroblasts, collagen, and elastin, helping to restore the extracellular matrix.
03High biocompatibility
& safety
Because it completely preserves its original structure, the HA avoids triggering the pro-inflammatory signals associated with modified or fragmented low molecular weight HAs (<20 kDa).
04Enhanced viscoelastic
behavior
Provides high clinical performance and rheological properties, maintaining a physical ‘water-filling’ effect with predictable degradation and longer-lasting aesthetic results.
Pillar 02 — Unmodified HA
Because the best version of you is always you, Wiotech’s hydric filling restores freshness, volume, and naturalness to your face.
By preserving the molecule’s native structure, our formulations achieve a viscosity up to 500 times higher than standard non-crosslinked market references. This translates into sustained hydration, a natural water-filling effect, and longer-lasting results.
With Wiotech’s hydric filling, restore freshness, volume, and naturalness to your face—because the best version of you is always you.
Evidence & R&D
Every claim is backed by physico-chemical and microbiological control and in-vitro data. We publish process and results, not promises.
0% <20 kDa
Zero generation of low molecular weight HA fragments (<20 kDa), preventing pro-inflammatory signaling and local immune activation.
835 – 24,000 mPa·s
Tailored viscosity range across our formulations (from HA MD 2 to HA MD 7), providing optimal resistance to degradation and displacement.
50-500x
Higher viscosity than market references, for greater degradation resistance and durability.
0
Out-of-spec residual BDDE, proteins or endotoxins in the finished, unmodified HA.
